Research to date shows that CBD is generally safe and has few, if any, minor side effects. But CBD does have the potential to interact with some medications, including the anticoagulant warfarin, the seizure medications valproic acid and clobazam. Similar to grapefruit, CBD inhibits the cytochrome P450 enzyme, which is involved in metabolizing many drugs. By inhibiting cytochrome P450, CBD can either reduce or increase the effects of other drugs. Please consult your physician if you have a health condition and/or are taking medications before taking CBD.